@media (min-width: 1600px) {
    #tabBitOne {
        top: 65px;
    }

    #tabBitTwo {
        top: 70px;
    }
}

@media (min-width: 768px) {
  .ring-bits,
  .small-bits {
        display: block;
    }

    .mb-md-19{
        margin-bottom: 19px;
    }
}

@media (min-width: 992px) {
  #tabBitOne,
  #tabBitTwo {
        display: block;
    }
.study4-section-desc{
    margin-left: 55px;
}
    /* navbar css start */
    .header-fixed {
        position: sticky;
        padding-top: 0;
        width: 100%;
        z-index: 99;
        transition: all 0.3s ease;
        /* padding-bottom: 50px; */
    }

        .header-fixed.hide {
            top: -143px;
        }

    /* .top-header {
    position: fixed;
    width: 100%;
    top: 0;
    z-index: 9999;
  } */
    .top-header {
        position: relative;
        z-index: 100;
    }

        .top-header .vl-right a:hover {
            color: var(--green-800);
        }

    .custom-nav .nav-item {
        border-right: 1px solid var(--green-600);
    }

        .custom-nav .nav-item:last-child {
            border-right: none;
        }

    .custom-nav .sub-menu {
        position: absolute;
        left: 0;
        width: 100%;
        display: none;
        top: 100%;
        background: rgba(208, 201, 184, 0.95);
    }

        .custom-nav .sub-menu li {
            border-bottom: 1px solid var(--green-600);
            padding: 10px 12px;
        }

            .custom-nav .sub-menu li:last-child {
                border-bottom: none;
            }

    .custom-nav .nav-item:hover {
        background-color: var(--green-600);
    }

        .custom-nav .nav-item:hover .sub-menu {
            display: block;
        }

    /* navbar css end */

    /* home page css start */
    .swiper-button-next,
    .swiper-button-prev {
        display: none;
    }

    .slider-section:after {
        bottom: 0;
    }

    .right_tabs .swiper-wrapper .swiper-slide:nth-child(3) {
        text-indent: 12px;
        margin-top: 5px;
        transform: translate(-2px, 10px);
    }

    .right_tabs .swiper-wrapper .swiper-slide:nth-child(2) {
        margin-top: 5px;
        transform: translate(11px, 5px);
    }

        .right_tabs .swiper-wrapper .swiper-slide:nth-child(2) .overview_tabbing p {
            padding-left: 12px;
        }

    .right_tabs .swiper-wrapper .swiper-slide:nth-child(1) {
        transform: translate(-12px, 5px);
        text-indent: -26px;
        margin-top: 4.75rem;
    }

    .theme-boxes li::before {
        content: "";
        width: 8px;
        height: 8px;
        position: absolute;
        left: 10px;
        top: 10px;
        border-radius: 5px;
        background-color: var(--primary-color);
    }

    .theme-boxes li::after {
        content: "";
        width: 100%;
        height: 15px;
        position: absolute;
        bottom: -10px;
        left: 0px;
        background: url(../images/box-shadow.svg) no-repeat;
    }

  .right_tabs
    .swiper-wrapper
    .swiper-slide:nth-child(1)
    .overview_tabbing::after {
        content: "";
        display: block;
        width: 40px;
        height: 56px;
        /*background-image: url(../images/dots-01.svg);
        background-repeat: no-repeat;
        background-size: contain;*/
        margin-left: 20px;
        margin-top: 5px;
    }

  .right_tabs
    .swiper-wrapper
    .swiper-slide:nth-child(2)
    .overview_tabbing::after {
        content: "";
        display: block;
        width: 33px;
        height: 56px;
        /* background-image: url(../images/dots-02.svg);
        background-repeat: no-repeat;
        background-size: contain;*/
        margin-top: 5px;
        margin-left: 5px;
    }

    /* home page css end */

    .main-title {
        position: relative;
        display: inline-block;
    }

        .main-title::before {
            position: absolute;
    content: "";
            background-image: url(../images/Dots-left.png);
            background-repeat: no-repeat;
            width: 40px;
            height: 21px;
            left: -50px;
            top: 50%;
            transform: translateY(-50%);
        }

        .main-title::after {
            position: absolute;
    content: "";
            background-image: url(../images/Dots-right.png);
            background-repeat: no-repeat;
            width: 53px;
            height: 21px;
            right: -60px;
            top: 50%;
            transform: translateY(-50%);
        }

    /* fixed slider css start */
    .fixed-slider .swiper-button-next,
    .fixed-slider .swiper-button-prev {
        display: block;
    }

        .fixed-slider .swiper-button-next:after,
        .fixed-slider .swiper-button-prev:after {
            font-size: 23px;
            font-weight: bold;
            color: var(--green-700);
        }

    /* fixed slider css end */

    /* how vpriv work section start */
    .how-vpriv-works-section .arrows::before {
        position: absolute;
        content: "";
        background-image: url(../images/arrow.svg);
        width: 100%;
        height: 11px;
        background-repeat: no-repeat;
        right: 35%;
        top: 50%;
        transform: translateY(-50%);
    }

    .how-vpriv-works-section .arrows::after {
        position: absolute;
        content: "";
        background-image: url(../images/arrow.svg);
        width: 100%;
        height: 11px;
        background-repeat: no-repeat;
        left: 70%;
        top: 50%;
        transform: translateY(-50%);
    }

    /* how vpriv work section end */

    /* table-section css start */
    .table-section .table-responsive {
        overflow-x: visible;
    }

    .table-section thead {
        position: relative;
        z-index: 1;
    }

        .table-section thead::before {
            position: absolute;
            width: calc(100% + 150px);
            height: 19px;
            content: " ";
        top: calc(100% - 1px);
            left: -75px;
            background-image: url(../images/table-shadow.png);
            background-repeat: no-repeat;
            background-size: 100%;
            background-position: top;
        }

    /* table-section css end */

    /* consider-vpriv section css start */
    .r-border {
        position: relative;
    }

        .r-border::after {
            position: absolute;
            content: "";
            height: 100%;
            width: 2px;
            background: #776f5a;
            right: -3px;
            opacity: 0.4;
        }

    .how-vpriv-works-section {
        position: relative;
    }

        .how-vpriv-works-section::before {
            position: absolute;
    content: "";
            background: linear-gradient(var(--theme-bg-dark-gradient));
            width: 100%;
            min-height: 380px;
            top: 80px;
        }

    /* consider-vpriv section css end */
}

@media (min-width: 1200px) {
    .container {
        max-width: 990px;
    }

    .sign-symptoms-section .mr-80 {
        margin-right: -80px;
    }
    .search-box {
        width: 92%;
    }
    .right_tabs .swiper-wrapper .swiper-slide:nth-child(3) {
        transform: translate(-25px, 10px);
    }

    /* navbar css start */
    .navbar-expand-lg .navbar-nav .nav-link {
        padding-left: 16px;
        padding-right: 16px;
    }

    .ss-banner {
        right: -7%;
        height: calc(100% + 20px);
        width: 45%;
        bottom: 0;
        position: absolute;
    }
    .vpriv-patient-population-section .pregnant-patients .ss-banner {
        right: -11%;
        width: 38%;
        top: 18%;
    }
    .vpriv-patient-population-section .older-patient .ss-banner {
        right: -5%;
        width: 25%;
        top: -27%;
    }
  .talk-to-ur-dr-section .ss-banner {
        right: -10%;
        width: 40%;
        height: auto;
        bottom: unset;
        top: 50%;
        transform: translateY(-50%);
    }
  .support-programs-section .ss-banner {
        height: auto;
        bottom: unset;
        top: 60%;
        transform: translateY(-50%);
        width: 43%;
    }
    /* navbar css start */

    .sign-symptoms-section .ss-banner{
        right: -11%;
        width: 50%;
    }
    .pediatric-patient-section .ss-banner {
        height: 100%;
        top: 30px;
        width: 38%;
    }
}

@media (min-width: 1300px) {
    .ss-banner {
        right: -15%;
        width: 50%;
    }
  .talk-to-ur-dr-section .ss-banner {
    right: -9%;
    width: 35%;
    }
  .vpriv-patient-population-section .older-patient .ss-banner {
        right: -2%;
        width: 25%;
        top: -12%;
    }
  .pediatric-patient-section .ss-banner {
        right: -5%;
        z-index: -1;
        width: 38%;
    }
  .pediatric-patient-section .row.position-relative {
        z-index: 1;
    }
    .support-programs-section .ss-banner {
        width: 50%;
    }
    .sign-symptoms-section .ss-banner{
        right: -15%;
        width: 52%;
    }
}

@media (min-width: 1400px) {
    .container {
        max-width: 990px;
    }

    .right_tabs .swiper-wrapper .swiper-slide:nth-child(3) {
        /* transform: translate(-24px, 5px); */
    }

    .footer-logo {
        position: absolute;
        right: -120px;
        bottom: 115px;
    }
}

@media (max-width: 1200px) {
    /* signs-symptopms page css start */
    .sign-symptoms-section::before {
        top: 0;
        height: 100%;
    }

    /* signs-symptopms page css end */
}

@media (max-width: 1199px) {
    .right_tabs .swiper-wrapper .swiper-slide {
        max-width: 250px;
    }
    .mb-xl-60{
        margin-bottom: 60px !important;
    }
}

@media (max-width: 1023px) {
    .fixed-slider {
        display: none;
    }

    .footer-inner {
        padding-bottom: 0 !important;
    }
}

@media (max-width: 991px) {
    .pr-50 {
        padding-right: 50px;
    }

    .bubble-img {
        height: 30px;
        width: auto;
    }
    .pb-lg-65{
        padding-bottom: 65px !important;
    }
    /* navbar css start */
    .custom-nav .navbar-toggler {
        position: fixed;
        right: 10px;
        top: 0;
        border-top-left-radius: 0;
        border-top-right-radius: 0;
        padding: 7px 5px;
        z-index: 99;
    }

        .custom-nav .navbar-toggler:focus {
            box-shadow: none;
        }

    .custom-nav .hamburger .line {
        width: 30px;
        height: 2px;
        background-color: var(--green-800);
        display: block;
        margin: 6px auto;
        -webkit-transition: all 0.3s ease-in-out;
        -o-transition: all 0.3s ease-in-out;
        transition: all 0.3s ease-in-out;
    }

    .custom-nav .hamburger:hover {
        cursor: pointer;
    }

    .top-header .vl-right {
        border-color: #ffffff;
    }

    #hamburger-1.is-active .line:nth-child(2) {
        opacity: 0;
    }

    #hamburger-1.is-active .line:nth-child(1) {
        -webkit-transform: translateY(13px) rotate(45deg);
        -ms-transform: translateY(13px) rotate(45deg);
        -o-transform: translateY(13px) rotate(45deg);
        transform: translateY(6px) rotate(45deg);
    }

    #hamburger-1.is-active .line:nth-child(3) {
        -webkit-transform: translateY(-13px) rotate(-45deg);
        -ms-transform: translateY(-13px) rotate(-45deg);
        -o-transform: translateY(-13px) rotate(-45deg);
        transform: translateY(-10px) rotate(-45deg);
    }

    .custom-nav .navbar-collapse {
        position: fixed !important;
        top: 0;
        right: 0;
        height: 100vh;
        background-color: var(--green-800);
        color: #ffffff;
        padding: 60px 20px;
        transform: translateX(100%);
        transition: all 0.3s linear;
    }

        .custom-nav .navbar-collapse.show {
            transform: translateX(0%);
            transition: all 0.3s linear;
        }

    .custom-nav .navbar-collapse.show ul {
        overflow-y: auto;
        height: 100%;
        } 

        .custom-nav .navbar-collapse a.text_green {
            color: #ffffff;
        }

        .custom-nav .navbar-collapse .nav-link {
            font-family: var(--font_Bebas_Neue);
            letter-spacing: 1px;
            font-size: var(--font-17);
            border-bottom: 1px solid;
        }

    /* navbar css end */

    /* homepage css start */
    .slider-acc-content {
        width: 100%;
        min-height: auto;
        height: 0;
        opacity: 0;
        visibility: hidden;
        transition: 0.3s auto;
    }

    .swiper-slide-thumb-active .slider-acc-content {
        visibility: visible;
        opacity: 1;
        height: auto;
        transition: 0.3s auto;
    }

    .slider-acc-content li {
        width: 100%;
        min-height: auto;
    }
  .slider-acc-content li p {
    margin-bottom: 0;
  }
        .slider-acc-content li a {
    width: auto;
            height: auto !important;
            border: 0px !important;
        }

  .home_slider
    .swiper-slide.swiper-slide-active:nth-child(1)
    .slider-acc-title {
        color: var(--primary-color);
    }

    .right_tabs {
        position: relative;
        width: 100%;
        transform: none;
    }

    .overview_tabbing p br {
        display: none;
    }

    .swiper-slide-thumb-active .overview_tabbing::after {
        content: "";
        background: url(../images/callout-shadow.png) no-repeat;
        background-position: center bottom;
        width: 83%;
        height: 14px;
        display: block;
        margin: 0 auto;
        background-size: 100%;
    }

    .overview_tabbing p {
        text-align: center;
    }

    .right_tabs .swiper-wrapper .swiper-slide {
        max-width: unset;
    }

        .right_tabs .swiper-wrapper .swiper-slide:not(:last-child) {
            border-bottom: 1px solid var(--green-600);
        }

        .right_tabs .swiper-wrapper .swiper-slide .overview_tabbing p {
            color: var(--green-700);
        }

    .content-toggle img {
        width: 15px;
    }

    .content-toggle {
        font-size: 13px;
        line-height: 1.5;
    }

    .important-sticky p,
    .important-short-content p,
    .important-short-content h6 {
        font-size: 12px;
        line-height: 1.2;
    }

    /* homepage css end */

    /* video-section css start */
    .video-section .video-main .video-link {
        padding: 10px;
    }

    .play-btn-icon {
        height: 52px;
        width: 52px;
    }

        .play-btn-icon img {
            width: 17px;
        }

    /* video-section css end */

    /* gaucher-disease css start */
    /* .chart-img-p-div img {
        width: 500px;
    } */

    .brief-about-gaucher .gaucher-dr {
        max-width: 270px;
        height: auto;
    }

    /* gaucher-disease css end */

    /* vpriv-patient-population-section css start */
    .vpriv-patient-population-section .py-40 {
        padding-top: 20px;
        padding-bottom: 20px;
    }

    /* vpriv-patient-population-section css end */

    /* diagnosis-disease-section css start */
    .diagnosis-disease-section .disease-monitoring-section::before {
        display: none;
    }

    /* diagnosis-disease-section css end */

    .how-vpriv-works-section .card-main .card-body::after {
        top: 98%;
    }

    .top-header .font-15 {
        font-size: 10px;
    }

    .custom-nav {
        padding: 0;
    }

    /* clinical-studies */
    .clinical-studies-section .common-box .card-title::after {
        width: calc(100% + 30px);
        left: -15px;
    }

    .clinical-studies-section .common-box .card-footer::before {
        width: calc(100% + 30px);
        left: -15px;
    }

    .clinical-studies-section .common-link {
        padding: 10px 20px;
}

    .clinical-studies-section .common-box .card-body {
        margin: 20px 0;
    }
  .mean-chart {
    width: calc(100% - 180px);
    }
    /* clinical-studies */
  .study2-section,
  .study4-newToVpriv-section,
  .study3-section,
  .study4-section,
  .study1-section {
    padding: 80px 0 60px;
  }
}
@media (max-width: 768px) {
.border-connect.study-4-border::before {
   
    right: -15%;
}
}

@media (max-width: 767px) {
  .custom-nav .navbar-collapse {
    padding: 30px 20px 50px;
  }
    /* homepage css start */
    .swiper-slide-thumb-active .overview_tabbing::after {
        height: 8px;
    }

    .slider-img {
        padding: 0 15px;
    }

    .right_tabs .swiper-wrapper .swiper-slide .overview_tabbing p {
        font-size: 20px;
    }

    /* homepage css start */

    /* video-section css start */
    .video-section .video-main .video-link {
        font-size: 12px;
        bottom: 20%;
    }

        .video-section .video-main .video-link span img {
            max-width: 15px;
        }

    /* video-section css end */
  .psm-div img {
        max-width: 50px;
        height: auto;
        align-self: flex-start;
    }
  .gaucher_community_sec .gaucher_box img {
        max-height: 70px;
        max-width: 200px;
    }
  .mean-chart {
    width: calc(100% - 200px);
    }
    .mean-chart-reponsive{
        width: 100%;
    }
    .w-48 {
        width: 100%;
    }

    .w-48.border-connect p {
        width: 48%;
        height: 100%;
    }

    .mobile_show img {
        transform: translateY(-50px);
        position: absolute;
        width: 160px;
    }

    .border-connect::before {
        width: 200px;
        top: -9%;
        right: 30%;
        left: auto;
        height: 72px;
        transform: translateY(0px);
    }

    .border-connect.study-1-border::before {
        background-image: url(../images/study1_connecting_lines_blue.svg);
    }
    .border-connect.study-2-border::before {
        background-image: url(../images/study1_connecting_lines_darkBlue.svg);
        /* left: 91%;
    top: 0;
    bottom: 0;
    background-size: 100%;
    margin: auto;
    width: 52px;
    height: 125px; */
    }
  .border-connect.study-4-border::before {
    width:52px;
    left: 92%;
    right: 0;
    top: 0;
    bottom: 0;
    margin: auto;
    height: 107px;
  }

    h3.study_graph_title,
    .study_graph_box1 {
        width: 51%;
        margin-right: 50px;
    }

  /* .study2-section,
    .study4-newToVpriv-section,
    .study3-section,
    .study4-section,
    .study1-section {
        padding: 100px 0 60px;
  } */

    .clinical-studies-section .common-box .card-body {
        margin: 15px 0;
  }
  .chart-img-p-div div:first-child img{
    width: 80%;
  }
  .chart-img-p-div div:last-child img:nth-child(2){
    margin-right: -25px;
  }
  
}

@media (max-width: 576px) {
    .bubble-img {
        height: 25px;
    }

    .slider-acc-content li a {
        font-size: 12px;
    }

  /* homepage css start */
  .swiper-slide-thumb-active .overview_tabbing::after {
    height: 8px;
  }

  .slider-img {
    padding: 0 15px;
  }

  .right_tabs .swiper-wrapper .swiper-slide .overview_tabbing p {
    font-size: 20px;
  }

  /* homepage css start */

  /* video-section css start */
  .video-section .video-main .video-link {
    font-size: 12px;
    bottom: 20%;
  }

  .video-section .video-main .video-link span img {
    max-width: 15px;
  }

  /* video-section css end */
  .psm-div img {
    max-width: 50px;
    height: auto;
    align-self: flex-start;
  }
  .gaucher_community_sec .gaucher_box img {
    max-height: 70px;
    max-width: 200px;
  }
  .w-42 {
    width: 47%;
  }

    /* .chart-img-p-div img {
        width: 300px;
    } */

    .brief-about-gaucher .gaucher-dr {
        max-width: 200px;
    }

    .video-section .video-main .video-link {
        font-size: 12px;
        width: 100%;
        padding: 5px 10px;
        bottom: 0;
        position: static;
    }

    .play-btn-icon {
        height: 32px;
        width: 32px;
    }

        .play-btn-icon img {
            width: 10px;
        }

  .top-header .font-15 {
        font-size: 10px;
    }

    .custom-nav .navbar-collapse {
        padding-right: 10px;
        padding-left: 10px;
    }

    .gaucher-diseases-section .img-chart-section::before {
        height: calc(100% - 20px);
    }

    .how-vpriv-works-section .card-img.px-4 img {
        width: 140px;
    }
  .gaucher-diseases-section .brief-about-gaucher .type-1-list p {
        font-size: 16px;
    }
  .gaucher-diseases-section .brief-about-gaucher h6 span {
        line-height: 34px;
    }
  .gaucher-diseases-section .brief-about-gaucher h6 b {
        font-size: 24px;
    }
  .gaucher-diseases-section .brief-about-gaucher h6 {
        line-height: 28px;
        font-size: 34px;
    }
    /* clinical studies*/
    .graph-value {
        height: 45px;
        width: 45px;
        line-height: 45px;
    }
  .graph-wrapper {
        height: 250px;
    }
  .graph-left-label,
  .graph-right-label {
        max-width: 60px;
    }
  .graph-left-label p,
  .graph-right-label p {
        font-size: 9px;
    }
    #headToHeadChart .graph-value {
        height: 25px;
        width: 25px;
        line-height: 25px;
        font-size: 12px;
    }

    h3.study_graph_title,
    .study_graph_box1 {
        margin-right: 10px;
    }

    .border-connect.study-2-border::before {
        right: 20%;
        width: 190px;
    }
    .up-arrow, .down-arrow{
        height: 45px;
        width: auto;
    }
    .graph-left-label img {
        margin-right: 5px;
    }
    .down-arrow {
        margin-left:5px;    
    }
    /* clinical studies*/
    .chart-img-p-div div:last-child img:nth-child(3) {
        margin-right: -15px;
    }  
    .chart-img-p-div div:last-child img:nth-child(2){
        margin-right: -15px;
    }  
}

@media (max-width: 420px) {
    .graph-value {
        height: 40px;
        width: 40px;
        line-height: 40px;
        font-size: 18px;
    }
    .custom-nav .navbar-collapse {
        padding-right: 10px;
        padding-left: 10px;
    }

    .border-connect.study-3-border p:first-child:after {
        width: 130px;
    }

    .study-3-border p:last-child {
        margin-top: 35px !important;
    }

    .border-connect::before {
        right: 20%;
    }

    .sitemap ul li .font-16 {
        font-size: 13px;
    }

    .modal-main .modal-dialog {
        margin-right: 15px;
        margin-left: 15px;
}

    .modal-main .custom-btn.font-16 {
        font-size: 10px;
    }
}

@media (max-width: 321px) {
    .mobile_show img {
        transform: translateY(-20px);
        position: absolute;
        width: 150px;
    }

    .study2-section,
    .study4-newToVpriv-section,
    .study3-section,
    .study4-section,
    .study1-section {
        padding: 80px 0 40px;
    }
}