@import url("variable.css");

body {
    font-family: var(--font_Nunito_Sans_Regular);
    color: var(--gray);
    background: linear-gradient(var(--theme-bg-gradient));
}

    body.overflow-hidden {
        /* padding-right: 15px; */
    }

:focus {
    outline: none;
    box-shadow: none;
}

a {
    display: inline-block;
    text-decoration: none;
    color: var(--primary-color);
}

    a:hover {
        color: var(--primary-color);
    }

/* navbar-css start */
.custom-nav {
  z-index: 99;
    padding: 16px 0 0;
  transition: 0.3s all ease-in-out;
}

    .custom-nav .nav-item a:hover {
        color: var(--purple-900);
        text-shadow: 0px 0px var(--purple-900);
    }

    .custom-nav .nav-item a.active {
        color: var(--purple-900);
        text-shadow: 0px 0px var(--purple-900);
        font-weight: bold;
    }

    .custom-nav .search-btn {
        width: 32px;
        height: 32px;
        border-radius: 50%;
    }

        .custom-nav .search-btn:hover {
            background-color: var(--purple-hover);
        }

            .custom-nav .search-btn:hover img {
  filter: invert(100%) sepia(0%) saturate(18%) hue-rotate(48deg)
    brightness(106%) contrast(103%);
            }

.top-header .vl-right {
    border-right: 1px solid #ffffff;
    white-space: nowrap;
}

.top-header .vl-right a {
    text-decoration: underline;
    text-underline-offset: 3px;
}

    .top-header .vl-right:last-child {
        border-right: none;
    }

.search-box {
    position: absolute;
    width: 86%;
    left: 0;
    border: 0;
    background-color: var(--green-400);
    border-radius: 25px;
    padding: 4px 0;
    text-indent: 40px;
    visibility: hidden;
}

    .search-box::placeholder {
        font-style: italic;
        font-family: var(--font_Nunito_Sans_Light);
        text-indent: 40px;
    }

.search-btn {
    position: relative;
    z-index: 99;
}

.search.open .search-box {
    visibility: visible;
    background-image: url("../images/search.svg");
    background-repeat: no-repeat;
    background-position: 15px;
}

.search .close-icon {
    display: none;
}

.search.open .close-icon {
    display: block;
}

.search.open .search-icon {
    display: none;
}

.custom-nav .search.open .search-btn:hover {
    background-color: transparent;
}

    .custom-nav .search.open .search-btn:hover img {
        filter: none;
    }

.navbar-nav.nav-hide {
    opacity: 0;
}

/* navbar-css end */

/* home slider start*/
.home_slider .swiper-slide {
    opacity: 0 !important;
}

    .home_slider .swiper-slide.swiper-slide-active {
        opacity: 1 !important;
    }

.home_slider {
    width: 100%;
    max-width: 100%;
}

.right_tabs {
    position: absolute;
    right: 0;
    z-index: 9;
    width: calc(100% - 660px);
  transform: translate(30px, 90px);
}

    .right_tabs .swiper-wrapper {
        flex-direction: column;
        overflow: visible;
    }

    .right_tabs .swiper {
        overflow: visible;
    }

    .right_tabs .swiper-wrapper .swiper-slide .overview_tabbing p {
        color: var(--green-300);
        cursor: pointer;
    }

.right_tabs
  .swiper-wrapper
  .swiper-slide.swiper-slide-thumb-active:nth-child(1)
  p {
        color: var(--primary-color);
    }

.right_tabs
  .swiper-wrapper
  .swiper-slide.swiper-slide-thumb-active:nth-child(2)
  p {
        color: var(--purple);
    }

.right_tabs
  .swiper-wrapper
  .swiper-slide.swiper-slide-thumb-active:nth-child(3)
  p {
        color: var(--accent-color);
    }

.theme-boxes li {
    width: 180px;
    min-height: 85px;
    max-width: 100%;
    position: relative;
}

    .theme-boxes li a {
        width: 180px;
        border-color: var(--green-200) !important;
        max-width: 100%;
    }

.slider-section:after {
    content: "";
    width: 100%;
    height: 26%;
    position: absolute;
    left: 0px;
    background: linear-gradient(var(--theme-bg-dark-gradient));
}

.theme-purple.theme-boxes li::before {
    background-color: var(--purple);
}

.theme-purple.theme-boxes li a:hover {
    color: var(--purple);
}

.theme-pink.theme-boxes li::before {
    background-color: var(--accent-color);
}

.theme-pink.theme-boxes li a:hover {
    color: var(--accent-color);
}
#persona0 .theme-boxes li a.active {
    color: var(--primary-color)
}
#persona1 .theme-boxes li a.active {
    color: var(--purple)
}
#persona2 .theme-boxes li a.active {
    color: var(--accent-color)
}
.safety-content ul li {
    border-color: var(--green-800) !important;
    line-height: 1;
}

.important-sticky {
    background-color: var(--green-800);
    z-index: 9;
}

.content-toggle {
    background-color: var(--green-800);
}

.important-short-content {
    left: 0;
    right: 0;
    z-index: 99;
    /* display: none; */
    transition: 0.3s all;
    height: 0;
}

    .important-short-content .container {
        background-color: var(--green-50);
    }

.inner-scroll-content {
    /* height: calc(100vh - 70px); */
    overflow: auto;
  border: 1px solid #6f6748;
    border-bottom: 0;
}

.short-content-visible {
    /* height: calc(100vh - 34px); */
    display: block;
    transition: 0.3s all;
}

/* home slider end*/

/* gaucher-diseases-section css start */
.gaucher-diseases-section {
    z-index: 5;
}

.fixed-slider.bottom-change {
    bottom: 0;
    transition: 0.3s all;
}

.gaucher-diseases-section .img-chart-section::before {
  position: absolute;
  content: "";
  background: linear-gradient(var(--theme-bg-dark-gradient));
  height: calc(100% - 30px);
  width: 100%;
  left: 0;
  z-index: -1;
  top: 0;
  bottom: 0;
  margin: auto;
}

.gaucher-diseases-section .brief-about-gaucher h6 {
    line-height: 46px;
    font-size: 52px;
}

.gaucher-diseases-section .brief-about-gaucher .type-1-list p {
    font-size: 20px;
    line-height: 1;
}

.gaucher-diseases-section .brief-about-gaucher h6 b {
    font-size: 32px;
}

.gaucher-diseases-section .brief-about-gaucher h6 span {
    display: inline-block;
    line-height: 46px;
}

/* gaucher-diseases-section css end */

/* video-section css start */
.video-section .video-main .video-link {
    position: absolute;
    bottom: 15%;
    right: 0;
    background-color: var(--accent-color);
    padding: 17px;
    transition: all 0.3s linear;
    z-index: 1;
}

.video-section .play-btn-icon{

        transition: all 0.3s linear;
    }
    /*.video-section .video-main .video-link:hover,.video-section .play-btn-icon:hover {
        background-color: var(--accent-hover);

    }*/

.video-section .video-main .video-link:active,.video-section .play-btn-icon:active {
  background-color: var(--accent-selected);
  transition: all 0.3s linear;
}

/* video-section css end */

/* sign-symptoms-section css start */
.common-symptoms-section .speak-comon {
    border: 1px solid #cac4b6;
    border-bottom: none;
    border-radius: 10px 10px 0px 0px;
    padding: 10px;
}

.common-symptoms-section .speak-cont {
    text-transform: uppercase;
}

.common-symptoms-section .symptom-patient-img {
    text-align: center;
}

/* sign-symptoms-section css end */

/* diagnosis-disease-section css start */
.chart-img-p-div{
    max-width: 730px;
    margin: 0 auto;
    align-items: center;
    padding: 0 25px;
}
.chart-img-p-div div:first-child{
    width:40%;
}
.chart-img-p-div div:last-child{
    width:60%;
    display: flex;
    flex-direction: column;
    align-items: flex-end;
}
.chart-img-p-div div:last-child img:nth-child(2){
    margin-right:-65px;
}
.chart-img-p-div div:last-child img:nth-child(3){
    margin-right:-25px;
}
.diagnosis-disease-section .disease-monitoring-section {
    z-index: 9;
}

.diagnosis-disease-section .disease-monitoring-section::before {
  position: absolute;
  content: "";
  background: linear-gradient(var(--theme-bg-dark-gradient));
  height: 280px;
  width: 100%;
  left: 0;
  z-index: -1;
  top: 20%;
}
/* .yt_thumbnail{
    position: absolute;
    top: 0;
    left: 0;
    z-index: 1;
} */
.yt_video{
    display: none;
}
/* diagnosis-disease-section css end */

/* fixed-slider css start */
.fixed-slider {
    bottom: 48px;
    z-index: 99;
    transition: 0.3s all;
}

    .fixed-slider .theme-boxes li::before {
        display: none;
    }

    .fixed-slider .theme-boxes li a {
        width: 100%;
    }

    .fixed-slider .theme-boxes li {
        width: 150px;
        min-height: 72px;
    }

    .fixed-slider .w-150 {
        width: 150px;
    }

    .fixed-slider .swiper-button-next:hover::after,
    .fixed-slider .swiper-button-prev:hover::after {
        color: var(--purple-hover);
        transition: all 0.3s linear;
    }

    .fixed-slider .swiper-button-next:after,
    .fixed-slider .swiper-button-prev:after {
        transition: all 0.3s linear;
    }

    .fixed-slider .swiper-slide {
        padding-top: 30px;
    }

        .fixed-slider #persona2.swiper-slide .w-150 {
            width: 182px;
            text-align: end;
        }

        .fixed-slider #persona2.swiper-slide .theme-boxes li {
            width: 186px;
        }

    .fixed-slider .swiper-wrapper {
        height: auto;
    }

    .fixed-slider .patient-img {
        position: relative;
        top: 1px;
    }

.swiper-button-next,
.swiper-button-prev {
    top: auto;
    bottom: 10px;
}

.fixed-slider::after {
    content: "";
    position: absolute;
    background-image: url(../images/fixed-slider-shadow.png);
    width: 960px;
    height: 15px;
    top: calc(100% - 101px);
    background-repeat: no-repeat;
    /* background-position-x: 420px; */
    background-size: cover;
    left: 50%;
    transform: translateX(-50%);
}

.fixed-slider::before {
    content: "";
    position: absolute;
    background: linear-gradient(var(--theme-bg-dark-gradient));
    width: 100%;
    height: calc(100% - 65px);
    bottom: 0;
}

.fixed-slider .theme-boxes li::after {
    display: none;
}

/* fixed-slider css end */



/* sign-symptoms-section css start */
.sign-symptoms-section {
    position: relative;
    z-index: 9;
}

.sign-symptoms-section::before {
  content: "";
  position: absolute;
  background: linear-gradient(var(--theme-bg-dark-gradient));
  height: 85%;
  width: 100%;
  z-index: -1;
  top: 6%;
}

/* sign-symptoms-section css end */


/* howvpriv-work-section css start */
.how-vpriv-works-section .ask-dr {
    border-bottom: 2px solid var(--primary-color);
}

.how-vpriv-works-section .card-main {
    border: 1px solid rgba(68, 54, 13, 0.12) !important;
    border-radius: 10px !important;
    border-bottom-left-radius: 0 !important;
    border-bottom-right-radius: 0 !important;
    flex: 1;
}

    .how-vpriv-works-section .card-main .card-body::after {
        position: absolute;
        content: "";
        background-image: url(../images/card-bottom-shadow.svg);
        width: 100%;
        height: 21px;
        background-repeat: no-repeat;
        right: 0;
        top: 99%;
        background-size: cover;
    }

    .how-vpriv-works-section .card-main .card-img {
        top: -20px;
    }

.how-vpriv-works-section .bg-custom-dark {
    position: relative;
}

    .how-vpriv-works-section .bg-custom-dark::after {
        position: absolute;
        content: "";
        background: linear-gradient(var(--theme-bg-dark-gradient));
    }

.how-vpriv-works-section .arrows {
    position: relative;
}

.how-vpriv-works-section .num-1 {
    height: 32px;
    width: 32px;
    border: 1px solid;
    border-radius: 50%;
    position: absolute;
    top: -5%;
    background: white;
    left: 15px;
}

/* howvpriv-work-section css end */





/* who-is-vpriv-for-section css start */
.who-is-vpriv-for-section .who-is-vpriv-main {
    z-index: 9;
}

    .who-is-vpriv-for-section .who-is-vpriv-main::before {
        position: absolute;
        content: "";
        background: linear-gradient(var(--theme-bg-dark-gradient));
        min-height: 378px;
        width: 100%;
        left: 0;
        z-index: -1;
        top: 0%;
        height: 100%;
    }

.vpriv-patient-population-section .pregnant-patients .box-border {
    border: 1px solid rgba(68, 54, 13, 0.12);
    border-radius: 25px;
}

/* who-is-vpriv-for-section css end */

/* table-section css start */
.table-section table {
  border: 1px solid rgba(68, 54, 13, 0.12);
    border-collapse: collapse;
  border-spacing: 0;
}

.table-section table td {
  border-left: 1px solid rgba(68, 54, 13, 0.12);
  border-bottom: 1px solid rgba(68, 54, 13, 0.12);
}

.table-section table td:first-child {
  border-left: 0;
}

.table-section table tr:last-child td {
  border-bottom: 0;
}

.table-section table {
  border-radius: 10px;
    border-collapse: separate;
}
.table-section .table > :not(caption) > * > * {
  padding: 5px 10px;
}

/* table-section css end */







.dwnload-btn {
    background-color: var(--purple-900);
}



.box-border {
    border: 1px solid rgba(68, 54, 13, 0.12);
    border-radius: 15px;
    border-bottom-left-radius: 0;
    border-bottom-right-radius: 0;
    border-bottom: 0;
}


.play-btn-icon {
    background-color: var(--accent-color);
    position: absolute;
    top: 50%;
    left: 50%;
    transform: translate(-50%, -50%);
    border-radius: 50%;
    height: 72px;
    width: 72px;
    display: flex;
    justify-content: center;
    align-items: center;
    z-index: 1;
}

.support-programs-section sup, .how-to-take-vpriv-section sup{
    top: -0.25em;
}
/* clinical studies */
.clinical-studies-section .common-box {
    /* border: 1px solid rgba(68,54,13,0.12); */
    border-radius: 10px;
}
.graph-wrapper {
    height: 300px;
    width: 90%;
    margin: 0 auto;
    position: relative;
}

.mean-chart, .mean-chart-reponsive {
  width: calc(100% - 120px);
}
.graph-div {
    display: flex;
    justify-content: space-around;
    height: 50%;
  position: relative;
  z-index: 1;
}

.graph-div-positive {
    align-items: flex-end;
  border-bottom: 2px dashed #5d4e62;
}

.graph-div-positive div {
    border-top-left-radius: 10px;
    border-top-right-radius: 10px;
}

.graph-div-negative div {
    border-bottom-left-radius: 10px;
    border-bottom-right-radius: 10px;
}

.mean-chart-div div {
    width: calc(100% / 5);
    position: relative;
    transition: all ease 1s;
    height: 0;
}

.mean-chart-div .graph-div-2value {
    display: flex;
    align-items: flex-end;
    height: 100%;
    justify-content: space-around;
    width: calc(100% / 4.6);
}

.graph-div-2value div {
    width: calc(100% / 2.1);
    height: 0px;
}

.graph-div-negative .graph-div-2value {
    align-items: flex-start;
}

.ticks {
    width: 100%;
    position: relative;
    height: 50%;
    z-index: 0;
    top: -100%;
}

.ticks div {
    height: 50%;
    position: relative;
    width: 100%;
    border-top: 1px solid rgba(123, 114, 96, 0.2);
}
.ticks.ticks-left div:first-child::before {
  content: "";
  top: 0;
  left: 0;
  width: calc(100% + 60px);
  height: 15px;
  background-position: bottom center;
  background-image: url("../images/graph-top-shadow.png");
  background-repeat: no-repeat;
  z-index: 10;
  background-size: contain;
  position: absolute;
  transform: translate(-30px, -100%);
}
.ticks.ticks-right div:last-child::before {
  content: "";
  top: 14px;
  left: 0;
  width: calc(100% + 60px);
  height: 15px;
  background-position: top center;
  background-image: url("../images/graph-bottom-shadow.png");
  background-repeat: no-repeat;
  z-index: 10;
  background-size: contain;
  position: absolute;
  transform: translate(-30px, -100%);
}
.ticks.ticks-left div:last-child {
    border-top: 0;
}

.ticks.ticks-right div:first-child {
    border-top: 0;
}

.ticks div p {
    position: absolute;
    top: -15px;
    margin: 0px;
    font-size: var(--font-20);
    text-align: right;
  color: #5d4e62;
    font-family: var(--font_Bebas_Neue);
}

.ticks-left div p {
    right: calc(100% + 15px);
}

.ticks-right div p {
    left: calc(100% + 15px);
}

.graph-value {
    position: absolute;
    left: 50%;
    /* transform: translate(-50%,0); */
    /* bottom: calc(100% + 15px); */
    margin: 0px;
    height: 55px;
    width: 55px;
    background: white;
    border-radius: 100%;
    line-height: 55px;
    font-size: var(--font-24);
    letter-spacing: -0.7px;
    font-family: var(--font_Bebas_Neue);
    border: 1px solid;
}

.graph-div-positive .graph-value {
    top: 0;
    transform: translate(-50%, -50%);
}

.graph-div-negative .graph-value {
    bottom: 0;
    transform: translate(-50%, 50%);
}

/* .graph-value::after {
    content: " ";
    width: 1px;
    height: 20px;
    border-left: 0.5px dashed;
    top: 100%;
    position: absolute;
    left: 50%;
} */

.graph-label {
    position: absolute;
    margin: 0px;
    width: 100%;
  color: #5d4e62;
    font-family: var(--font_Nunito_Sans_Regular);
    font-size: var(--font-16);
}

.graph-div-positive .graph-label {
    top: calc(100% + 12px);
}

.graph-div-negative .graph-label {
    top: calc(100% + 40px);
}

.graph-left-label {
    position: absolute;
    right: calc(100% + 35px);
    top: 50%;
    display: flex;
    align-items: flex-end;
    justify-content: center;
    flex-direction: column;
    transform: translateY(-100%);
    width: 100%;
    max-width: 110px;
}

.graph-left-label img {
    margin-bottom: 8px;
    margin-right: 10px;
}

.graph-left-label p {
  color: #5d4e63;
    font-size: var(--font-12);
    /* transform: rotate(
-90deg) translate(-50%, -300%); */
    text-align: right;
    margin: 0px;
    font-weight: bold;
    font-family: var(--font_Nunito_Sans_Regular);
}

.graph-right-label {
    position: absolute;
    top: 50%;
    display: flex;
    align-items: flex-start;
    justify-content: center;
    flex-direction: column;
    z-index: 1;
    left: calc(100% + 35px);
    width: 100%;
    max-width: 100px;
}
.graph-right-label p {
    right: 0px;
    /* transform: rotate( 90deg) translate(50%, -400%); */
    margin: 0px;
    text-align: left;
  color: #5d4e63;
    font-size: var(--font-12);
    font-weight: bold;
    font-family: var(--font_Nunito_Sans_Regular);
}


.down-arrow {
    margin-top: 8px;
    margin-left: 10px;
}


.subset-graph {
    position: relative;
  border-bottom: 1px solid #5d4e62;
}

.subset-graph::after {
    content: "";
    height: calc(100% + 15px);
    width: 1px;
  background: #5d4e62;
    position: absolute;
    left: 50%;
    top: 0px;
}

.bar-hor-positive {
    border-top-right-radius: 20px;
    border-bottom-right-radius: 20px;
    height: 70px;
    box-shadow: 0px 3px 6px #00000080;
    position: relative;
    width: 0px;
    transition: all ease 1s;
}

.bar-hor-negative {
    border-top-left-radius: 20px;
    border-bottom-left-radius: 20px;
    height: 70px;
    box-shadow: 0px 3px 6px #00000080;
    position: relative;
    width: 0px;
    transition: all ease 1s;
}

.bar-ticks p {
    width: 32px;
    text-align: center;
    margin: 0px;
    margin-top: 14px;
    position: relative;
}

.bar-ticks .tick-none::after {
    content: none;
}

.bar-ticks p::after {
    content: "";
    position: absolute;
    bottom: 100%;
    height: 15px;
    left: 52%;
    width: 1px;
  background: #5d4e62;
}

.bar-ticks p:first-child::after {
    left: 0;
}

.bar-ticks p:last-child::after {
    left: 100%;
}


.arrow-graph {
    position: absolute;
    display: flex;
    align-items: center;
    justify-content: center;
    width: 54px;
    height: 54px;
    top: -20px;
    border-radius: 100%;
    background: white;
    box-shadow: 0px 3px 6px #0000004d;
    font-size: var(--font-25);
}

.postive-graph-arrow {
    left: calc(100% - 27px);
}

.negative-graph-arrow {
    right: calc(100% - 27px);
}

.extra-label {
    position: absolute;
    width: 100%;
    bottom:0;
    right:0;
    max-width: 200px;
}

.last-value::before {
    content: "*";
    bottom: 55%;
    left: 80%;
    font-size: 16px;
    line-height: 12px;
    position: absolute;
}

.highcharts-credits {
    display: none;
}

/* .tabs {
    transition: all ease 0.3s;
} */
.yAxis-responsive-title {
    color: #333333;
    cursor: pointer;
    font-size: 12px;
    font-weight: bold;
    fill: #333333;
}

.search-results,
.search-results1 {
    overflow: auto;
}

.patient-story-img {
    height: auto;
}
.clinical-studies-section .common-link {
    padding: 10px 40px;
    border-radius: 5px;
  }

.endpoint-header::after{
    width: 50px;
    height: 2px;
    border-radius: 20px;
    background: var(--gray);
    content: "";
    position: absolute;
    left: 0px;
    top: calc(100% + 5px);
}
.clinical-studies-section .common-box .top-border {
  border: 1px solid rgba(68, 54, 13, 0.12);
    border-radius: 10px 10px 0 0;
    border-bottom: 0;
  }
.clinical-studies-section .common-box .card-title {
    position: relative;
  }
.clinical-studies-section .common-box .card-title::after {
    position: absolute;
    content: "";
    background-image: url(../images/topshadow.png);
    height: 100%;
    width: calc(100% + 80px);
    background-repeat: no-repeat;
    background-size: contain;
    left: -40px;
    bottom: 0;
    background-position: bottom;
  }
.clinical-studies-section .common-box .card-body {
  margin: 25px 0;
  border-left: 1px solid rgba(68, 54, 13, 0.12);
  border-right: 1px solid rgba(68, 54, 13, 0.12);
  }
.clinical-studies-section .common-box .card-body .common-link {
  margin: 15px 0 5px;
  }
.clinical-studies-section .common-box .card-body .border-right {
  border-right: 1px solid rgba(68, 54, 13, 0.12);
  }
.clinical-studies-section .common-box .card-body .border-left {
  border-left: 1px solid rgba(68, 54, 13, 0.12);
  }
.clinical-studies-section .common-box .card-footer {
  border: 1px solid rgba(68, 54, 13, 0.12);
    border-radius: 0 0 10px 10px;
    border-top: 0;
    position: relative;
  padding: 20px 0;
  }
.clinical-studies-section .common-box .card-footer::before {
      position: absolute;
      content: "";
      background-image: url(../images/bottomshadow.png);
      height: 19px;
      width: calc(100% + 80px);
      background-repeat: no-repeat;
      background-size: contain;
      left: -40px;
      top: 0;
  }
.clinical-studies-section .sqaure-box-border {
  border: 1px solid rgba(68, 54, 13, 0.12);
    border-radius: 10px;
  }
  .clinical-studies-section .common-box .card-body {
    vertical-align: middle;
    display: flex;
    align-items: center;
    flex-direction: column;
    justify-content: space-between;
}
.border-connect {
    position: relative;
  }
.border-connect::before {
    position: absolute;
  content: "";
    /* background-image: url("../images/study-1-border.svg"); */
    background-repeat: no-repeat;
    /* width: 25px;
    height: 100%;
    background-position: center;
    background-size: contain;
    left: -7%;
    top: 50%;
    transform: translateY(-50%); */
    width: 45px;
    height: 100%;
    background-position: center;
    background-size: contain;
    left: -16%;
    top: 45%;
    transform: translateY(-45%);
  }
.w-48 {
    width: 48%;
    flex: 0 0 auto;
  }
.w-42 {
    width: 42%;
    flex: 0 0 auto;
  }
.study4-section-title {
    margin-left: 55px;
  }
.border-connect.study-1-border::before {
    background-image: url(../images/study-2-border.svg);
  }
.border-connect.study-2-border::before {
    background-image: url(../images/study-2-border-2.svg);
  }
.border-connect.study-4-border::before {
    background-image: url(../images/study-4-border.svg);
    left: unset;
    right: -17%;
  }
.border-connect.study-3-border p:first-child:after {
    background-image: url(../images/study-3-border.png);
    width: 180px;
    height: 54px;
    left: 50%;
    transform: translateX(-50%);
    top: 100%;
    content: "";
    background-size: contain;
    background-repeat: no-repeat;  
    position: absolute;
  }
.border-connect.study-4-2-border p:first-child:after {
    background-image: url(../images/study-4-newToVpriv.svg);
    width: 9px;
    height: 37px;
    left: 50%;
    transform: translateX(-50%);
    top: calc(100% - 4px);
    content: "";
    background-size: contain;
    background-repeat: no-repeat;
    position: absolute;
  }
.study-4-2-border .pink-border {
    position: relative;
  }
.study-4-2-border .pink-border::before {
    position: absolute;
    content: "";
    height: 12px;
    width: 100%;
    background-color: var(--accent-color);
    bottom: 0;
    left: 0;
    border-radius: 0 0 15px 15px;
  }
.study-4-2-border .green-border {
    position: relative;
    margin-top: 27px;
  }
.study-4-2-border .green-border::before {
    position: absolute;
    content: "";
    height: 12px;
    width: 100%;
    background-color: var(--green);
    bottom: 0;
    left: 0;
    border-radius: 0 0 15px 15px;
  }
  
.clinical-studies-section .bg-dark-gradient {
   z-index: 1;
  }
.clinical-studies-section .bg-dark-gradient::before {
    position: absolute;
    content: "";
    background: linear-gradient(var(--theme-bg-dark-gradient));
    width: 100%;
    height: calc(100% - 60px);
    z-index: -10;
    top: 50%;
    left: 0;
    transform: translateY(-50%);
  }
/* clinical studies */

.form-control {
    border-color: var(--gray);
}

.unsubscribe_form input.input-validation-error,
.unsubscribe_form .input-validation-error .form-select,
.captcha-invalid > div {
    border: 1px solid #dc3545 !important;
}

/* Home page slider animation */
.ring-bits {
    width: 572px;
    position: absolute;
  top: 0px;
    left: 141px;
    display: none;
  padding-top: 3rem;
}

.small-bits {
    height: auto;
    position: absolute;
    left: 0;
    height: auto;
    display: none;
}

#leftBubbleBit {
    width: 70px;
  top: 120px;
    left: 25px;
}

#tabBitOne {
    width: 50px;
    top: 57px;
    display: none;
}

#tabBitTwo {
    width: 50px;
    top: 57px;
    left: -15px;
    display: none;
}

.ring-bits img,
.small-bits img {
    position: absolute;
    width: 100%;
    display: none;
}

.ring-bits img.show,
.small-bits img.show {
    display: block;
}


/* stayupdate-form css start */
.stayupdate-form .dropdown-toggle::after {
    position: absolute;
    top: 50%;
    transform: translateY(-50%);
    right: 10px;
}
.stayupdate-form a.dropdown-toggle:hover {
    border: 1px solid;
}
.stayupdate-form .resize-none {
    resize: none;
}
.stayupdate-form .select-arrow {
    background-image: url("../images/dropdown.svg");
    background-repeat: no-repeat;
    background-position: center right 10px;
}

.stayupdate-form input.input-validation-error,
.stayupdate-form select.input-validation-error,
.captcha-invalid > div {
    border: 1px solid #dc3545 !important;
}
/* stayupdate-form css end */

/* downloadable-resources */
.downloadDetail {
    padding: 0 36px;
}
/* downloadable-resources */

/* .swiper-slide-duplicate .ring-bits{
    display: none;
} */
/* faq */
.accordion-item{
    border-bottom: 1px solid rgba(68, 54, 13, 0.12);
}
.accordion-header{
    display: flex;
    /* align-items: center; */
    justify-content: space-between;
    cursor: pointer;
    line-height: 24px;
}
.accordion-header img{
    margin-left: 10px;
    align-self: flex-start;
}
.accordion-header.collapsed:hover {
  background: linear-gradient(0deg, #cfcdc1, #cfcdc1),
    linear-gradient(0deg, #d0c9b8, #d0c9b8);
}
.accordion-header:hover{
    background: transparent;
}
.accordion-header.collapsed .tabPlus{
    display: block;
}
.accordion-header .tabPlus{
    display: none;
}
.accordion-header.collapsed .tabMinus{
    display: none;
}
.accordion-header .tabMinus{
    display: block;
}
.accordion-body{
    padding-bottom: 20px;
}

.slider-acc-content li {
  /* display: none; */
  height: 0;
  width: 0;
  opacity: 0;
  visibility: hidden;
  transition: 0.4s all;
}
.swiper-slide-thumb-active .slider-acc-content li {
  /* display: block; */
  height: auto;
  width: auto;
  opacity: 1;
  visibility: visible;
  transition: 0.4s all;
}

.isi-overlay {
    content: "";
    width: 100%;
    height: 100%;
    background: transparent;
    position: fixed;
    top: 0;
    left: 0;
    z-index: 99;
    display: none;
}
/* modal-box css start */
.modal-main .modal-dialog{
    max-width: 400px;
    margin-right: auto;
    margin-left: auto;
}
.modal-main .modal-content{
    border-color: #6F6748;
    border-end-start-radius: 0;
    border-bottom-right-radius: 0;
}
.modal-main .btn-close{
    position: absolute;
    right: 25px;
    top: -8px;
    background: white;
    border-radius: 50%;
    opacity: 1;
    padding: 0;
    height: 26px;
    width: 26px;
    border: 1px solid #6F6748;
}
.modal-main .custom-btn{
    max-width: 168px;
    width: 100%;
}
.modal-main .border-btn{
    border: 1px solid;
}
.modal-main .btn-blue{
    border: 1px solid var(--primary-color);
    color: #ffffff;
}
.modal-main .btn-blue:hover{
    color: var(--primary-color);
}
.modal-main .btn-pink{
    border: 1px solid var(--accent-color);
    color: #ffffff;
}
.modal-main .btn-pink:hover{
    color: var(--accent-color);
}
.modal-main .border-btn:hover{
    background-color: var(--green-900);
    border-color: var(--green-900);
    color: #ffffff;
}
.modal-main .popupshadow{
    transform: translate(-50px , 94%);
    width: calc(100% + 100px);
}

#personaRing3 {
  transform: rotate(-15deg);
  left: 42px;
}
.sitemap hr{
    border-color: #CFCDC1;
    opacity: 1;
}
.sitemap ul li::marker{
    color: var(--primary-color);
}
body.x.modal-open {
  overflow-y: auto !important;
}

.highcharts-background{
  fill: transparent;
}
.highcharts-axis-line{
  stroke: #695e3c80;
}

.highcharts-legend-item .highcharts-graph, .highcharts-legend-item .highcharts-point{
  display: none;
}
.highcharts-legend-item text{
  text-transform: uppercase;
}
.highchartText{
    width: 85%;
    margin-left: auto;
}
.highchartText sup{
    font-size: 0.6em;
}
.highcharts-yaxis-labels{
  font-family: "Bebas-Neue";
}
.table-section th.header2 {
  font-size: 20px;
  line-height: 1;
}
.dashLine{
  padding-left: 20px;
  position: relative;
}
.dashLine::before{
  position: absolute;
  content: "";
  width: 13px;
  height: 5px;
  border-radius: 10px;
  left: 0;
  top: 10px;
  background-color: inherit;
}
.dashLine.dashLinepurple::before{
  background-color: var(--purple);
}
.dashLine.dashLinegreen::before{
  background-color: var(--green);
}
.dashLine.dashLineblue::before{
  background-color: var(--primary-color);
}
.dashLine.dashLinepink::before{
  background-color: var(--accent-color);
}
#LongTermChart, #LongTermExtChart, #switchStudychart{
  position: relative;
}
#LongTermChart::before, #LongTermExtChart::before, #switchStudychart::before{
  content: "";
  top: 0;
  left: 0;
  width: 100%;
  height: 19px;
  background-position: center;
  background-image: url("../images/graph-top-shadow.png");
  background-repeat: no-repeat;
  z-index: 9;
  background-size: contain;
    position: absolute;
}
#LongTermChart::after, #LongTermExtChart::after, #switchStudychart::after{
  content: "";
  bottom: 0;
  left: 0;
  width: 100%;
  height: 19px;
  background-position: center;
  background-image: url("../images/graph-bottom-shadow.png");
  background-repeat: no-repeat;
  z-index: 9;
    position: absolute;
    background-size: contain;
}

.search-result{
    position: absolute;
    width: 100%;
    left: 0;
    top: 100%;
}
.search-result .searchList{
    margin-bottom: 2px;
}
.search-result-list{
    max-height: 300px;
    overflow-y: auto;
}
.highcharts-text-outline{
    stroke: none;
    fill: none;
}
.person_img img {

   height: auto;
  
   display: none;
  
   width: 100%;
  
   height: auto;
  
  }
  
  .person_img img.show {
  
   display: block;
  
  }